Cambridge 劍橋 CANTAB 測驗 - PAL 關聯配對學習測驗

產品型號: PAL
廠牌名稱: Cambridge Cognition
關聯配對學習測驗（Paired Associates Learning）
CANTAB 劍橋認知心理衡鑑系統中的視覺記憶測驗之一

# 認知測驗 # CANTAB

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簡介：關聯配對學習測驗（Paired Associates Learning，PAL）可評估視覺記憶和學習新事物的能力，在評估可能的失智、輕度認知功能障礙、阿茲海默症以及與年齡相關的記憶損傷上是相當有用的工具。
施測時間：大約 8 分鐘，視實際情況而定。
作業：螢幕畫面上的方塊會隨機地開啟，其中一個或多個方塊中會有一個圖形。接著這些圖形會一次一個地顯示在螢幕中間，受測者需要觸碰該圖形原來所在的方塊。若受測者做了錯誤的選擇，則該圖形會再一次地出現，以提醒受測者其所在的位置。隨著測驗的進行，難度會逐漸增加。亦可使用較高難度的版本來測試高功能或健康的個體。
測驗結果：包括受測者的錯誤次數、正確指出圖形位置所需的次數、記憶分數和完成的階段…等。

相關型錄/資訊

CANTAB Connect Research 劍橋神經認知測驗介紹

主要參考文獻

CANTAB Alzheimer’s (Dementia) Battery

Fowler KS, Saling MM, Conway EL, Semple JM, Louis WJ. Paired associate performance in the early detection of DAT. Journal of the International Neuropsychological Society : JINS. 2002;8(1):58-71.
Egerhazi A, Berecz R, Bartok E, Degrell I. Automated Neuropsychological Test Battery (CANTAB) in mild cognitive impairment and in Alzheimer’s disease. Progress in neuro-psychopharmacology & biological psychiatry. 2007;31(3):746-51. Epub 2007/02/10.
Blackwell AD, Sahakian BJ, Vesey R, Semple JM, Robbins TW, Hodges JR. Detecting dementia: novel neuropsychological markers of preclinical Alzheimer’s disease. Dement Geriatr Cogn Disord. 2004;17(1-2):42-8. Epub 2003 Oct 13.
Greig NH, Sambamurti K, Yu QS, Brossi A, Bruinsma GB, Lahiri DK. An overview of phenserine tartrate, a novel acetylcholinesterase inhibitor for the treatment of Alzheimer’s disease. Curr Alzheimer Res. 2005;2(3):281-90.
Atack JR. Preclinical and clinical pharmacology of the GABAA receptor alpha5 subtype-selective inverse agonist alpha5IA. Pharmacology & therapeutics. 2010;125(1):11-26. Epub 2009/09/23.

CANTAB Schizophrenia Battery

Barnett JH, Robbins TW, Leeson VC, Sahakian BJ, Joyce EM, Blackwell AD. Assessing cognitive function in clinical trials of schizophrenia. Neurosci Biobehav Rev. 2010 Jul;34(8):1161-77. doi: 10.1016/j.neubiorev.2010.01.012. Epub 2010 Jan 25.
Joyce E, Hutton S, Mutsatsa S, Gibbins H, Webb E, Paul S, Robbins T, Barnes T. Executive dysfunction in first-episode schizophrenia and relationship to duration of untreated psychosis: the West London Study. Br J Psychiatry Suppl. 2002 Sep;43:s38-44.
Saleem MM, Harte MK, Marshall KM, Scally A, Brewin A, Neill JC. First episode psychosis patients show impaired cognitive function--a study of a South Asian population in the UK. J Psychopharmacol. 2013 Apr;27(4):366-73. Epub 2013 Feb 20.
Zhornitsky S, Aubin G, Desfossés J, Rizkallah E, Pampoulova T, Lipp O, Chiasson JP, Stip E, Potvin S. Predictors of community functioning in schizophrenia and substance use disorder patients. Community Ment Health J. 2013 Jun;49(3):317-22. Epub 2012 Jul 31.
Levkovitz Y, Mendlovich S, Riwkes S, Braw Y, Levkovitch-Verbin H, Gal G, Fennig S, Treves I, Kron S. A double-blind, randomized study of minocycline for the treatment of negative and cognitive symptoms in early-phase schizophrenia. J Clin Psychiatry. 2010 Feb;71(2):138-49. Epub 2009 Nov 3.

Cantab Depression Battery

Rock PL, Roiser JP, Riedel WJ, Blackwell AD. Cognitive impairment in depression: a systematic review and meta-analysis. Psychol Med. 2013 Oct 29:1-12. [Epub ahead of print]
Roiser JP, Sahakian BJ. Hot and cold cognition in depression. CNS Spectr. 2013 Jun;18(3):139-49.
Egerházi A, Balla P, Ritzl A, Varga Z, Frecska E, Berecz R. Automated Neuropsychological Test Battery in depression -- preliminary data. Neuropsychopharmacol Hung. 2013 Mar;15(1):5-11.
Greer TL, Sunderajan P, Grannemann BD, Kurian BT, Trivedi MH. Does duloxetine improve cognitive function independently of its antidepressant effect in patients with major depressive disorder and subjective reports of cognitive dysfunction? Depress Res Treat. 2014;2014:627863.
van Tol MJ, van der Wee NJ, Demenescu LR, Nielen MM, Aleman A, Renken R, van Buchem MA, Zitman FG, Veltman DJ. Functional MRI correlates of visuospatial planning in out-patient depression and anxiety. Acta Psychiatr Scand. 2011 Oct;124(4):273-84.
Papakostas GI. Cognitive symptoms in patients with major depressive disorder and their implications for clinical practice. J Clin Psychiatry. 2014 Jan;75(1):8-14.

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